Lot
4317 
(Route 5032) Cincinnati & Louisville Mail Route, cds cancels 3¢ red Nesbitt buff entire to Pittsburgh Pa.; stain at bottom left, otherwise Very Fine. Milgram No. O-21-a Estimate $200 - 300.
This cover probably put onto Route 5032 at Louisville and transferred at Cincinnati to the post roads running east to Pittsburgh. There was no continuous route by water that was contracted on the Ohio River between Cincinnati and Pittsburgh.